Binge drinking-induced liver injury

Small heterodimer partner deficiency exacerbates binge drinking-induced liver injury via modulation of natural killer T cell and neutrophil infiltration

Binge drinking among alcohol consumers is a common occurrence, and may result in the development of numerous diseases, including liver disorders. It has previously been reported that natural killer T (NKT) cells induce alcohol‑associated liver injury by promoting neutrophil infiltration. In the present study, the role of the orphan nuclear receptor small heterodimer partner (SHP), which is enco...

Binge drinking and nitric oxide metabolites in chronic liver disease.

AIMS The effect of binge drinking in the production of nitric oxide metabolites has not been studied in patients with chronic viral liver disease. METHODS We therefore studied serum levels of nitrites and nitrates (NOx) in 13 patients with chronic viral hepatitis and nine patients with compensated viral cirrhosis, after administration of 80 g alcohol. 15 patients with compensated alcoholic ci...

Smoking, Binge Drinking and the

Fraternity membership and binge drinking.

This paper examines the relationship that social fraternity and sorority membership has with binge drinking incidence and frequency among 18-24 year old full-time 4-year college students who participated in the 1995 National College Health Risk Behavior Survey. To net out unobserved heterogeneity, several measures of situational and total alcohol use are entered into the regressions as explanat...

Binge Drinking and Public Health

Alcohol misuse, in the form of binge drinking (BD), is prevalent among young people and seems to be a distinctive characteristic of the British drinking culture. Over the last 2 years the Government has reformed licensing laws and implemented a strategy aimed at reducing alcohol-related harm. This briefing describes the extent of BD in the UK, examines the current legislation and analyses the p...